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Perioperative nutritional care in patients undergoing radical cystectomy for bladder cancer
Slanařová, Barbora ; Staník, Michal (advisor) ; Furdek, Michal (referee)
Perioperative nutritional care is an integral part of the management and accelerated recovery program after radical cystectomy. Currently, there is limited literature dealing about perioperative nutritional care in patients undergoing radical cystectomy for bladder cancer. The purpose of the practical part was to determine the effect of preoperative immunomodulating nutrition of ONS type on the postoperative complications and the length of stay in hospital in 25 patients undergoing radical cystectomy for bladder cancer at the Masaryk Memorial Cancer Institute in 2022, compared to 32 patients without preoperative immunomodulating nutrition who underwent radical cystectomy in 2021. The second efficacy point of the practical part was to investigate the process of specialised perioperative nutritional care held according to a specialised protocol involving patients undergoing radical cystectomy for bladder cancer and to propose a modification of the process in order to improve the quality of nutritional care provided in perioperative period. In our research, preoperative immunomodulating nutrition of ONS type did not significantly affect postoperative complications and length of stay in hospital compared to the retrospective control group without preoperative immunomodulating preparation. Further...
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Immunochemical determination of active and inactive form of cathepsin B in patients with bladder cancer
Urban, Tomáš ; Bosáková, Zuzana (advisor) ; Klapková, Eva (referee)
This thesis is focused on immunochemical determination of concentration of active and inactive form of cathepsin B in patients with bladder cancer in order to compare diagnostic efficiency of methods for their possible use for routine diagnosis. Cathepsin B and procathepsin B were measured in serum and urine in 82 patients with bladder cancer (47 men and 35 women), with the average age of 66.5 year. The control group contain of 72 healthy subjects (31 men and 41 women), with the average age of 58.5 year. The concentration of cathepsin B and procathepsin B in the urine were corrected to creatinine, which was determined by the enzymatic creatinase method. The concentrations of cathepsin B in urine were singnificantly elevated in patients than in control group (median = 3.5 µg/l vs. 0.9 µg/l, P = 0.01), similarly the results of the cathepsin B/creatinine ratio were elevated (median = 0.4 µg/mmol vs. 0.1 µg/mmol, P = 0.01). There were no significant difference in concentration in serum between patients and control group (median = 4.8 µg/l vs. 4.2 µg/l, P = 0.8). The concentration values of procathepsin B were significantly higher in patients compare to control group both in urine (median = 3.9 µg/l vs. 1.4 µg/l, P < 0.0001), in serum (median = 73.3 µg/l vs. 58.7 µg/l, P = 0.0005) and similarly in...
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Nursing care of patiens undergoing cystoscopic follow-up
MAŠÍKOVÁ, Kateřina
The subject of this bachelor work is Nursing care of patients undergoing permanently cystoscopic follow-up. The thesis is divided into two parts. The theoretical part is devoted to the problem of providing nursing care to patients witch bladder cancer who untergo regular cystoscopic controls. It describes characteristics of the malignancy of the urinary bladder and its treatment, system of cystoscopic controls, awereness and nursing care for these patients. We have identified six objectives for this work. The first objective was to determine whether the patients have information about cystoscopic examination. The second objective was to determine whether the patients have information on duration of cystoscopic follow-up. The third objective was to map the most common complications after the cystoscopic examinations from the perspective of the patient. The forth objective was to map nursing practice of nurses in the care of permanently cystoscopic follow-up patients. The fifth objective was to determine whether the nurses know the specifics of nursing care for permanently cystoscopic followed-up patients. The last objective was to map the most common complications after the cystoscopic examination from the perspective of nurses. In the empirical part we set three hypotheses and three research questions. The first hypothesis was that patients have information about cystoscopic examination. The second hypothesis was that patients have the information on the length of cystoscopic follow-up. The third hypothesis stated that patients report as the most common complication after examination cystoscopic dysuriac problems. The first research question was what are the procedures for nurses in the nursing care of patients cystoscopic followed-up patients at selected locations. The second research question was what are the specifics of the nursing care of permanently cystoscopic follow-up patients from the perspective of nurse. The third research question was what are the most common complications after cystoscopic examination from the perspective of nurses. Based on an anonymous evaluation questionnare, the first, second and third hypothesis are confirmed and all the research questions were answered on the basic of interviews witch nurses. To obtain information from patients who are permanently cystoscopic followed-up at hospital departments of urology Nemocnice České Budějovice, a.s. and Nemocnice Písek a.s. (=Hospital, a.s. joint-stock company) was used a quantitative method for date collection through an anonymous questionnaire. The questionnare contained 25 closed and semi-open questions. A total of 120 questionnaires were distributed of whitch the final survey used research of 82 ones. Survey results are summarized in graphs. Nonstandardized interview questioning technique witch nurses was used for data collection of quantitative research method. Getting information from the nurses was carried out through depth interview and was by means questions prepared in advance. Research survey was attended by 8 nurses working in hospital department of urology in Nemocnice České Budějovice a.s. and Nemocnice Písek a.s. Interviews with nurses were drawn for charity in case reports. Discussion was confronted with the specialized literature. The outcome of this bachelor work is the information booklet for permanently cystoscopic followed-up patients.
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